bandshift assay

English

Noun

bandshift assay (plural bandshift assays)

1. (biochemistry) A type of assay using gel electrophoresis, in which the mobility of a DNA or RNA probe alone is compared to its mobility in combination with a particular protein, so as to measure the degree and nature of binding between the protein and DNA or RNA.
   • 2001 May 11, Peter Baumann, Thomas R. Cech, “Pot1, the Putative Telomere End-Binding Protein in Fission Yeast and Humans”, in Science‎^[1], volume 292, number 5519, →DOI, pages 1171–1175:

     In bandshift assays, hPot1p bound to the G-rich strand of human telomeric DNA.

See also

• Electrophoretic mobility shift assay on Wikipedia.Wikipedia